Your doctor may adjust your dose as needed. Comments: Child dosage (ages 0–5 years) This drug shouldn’t be used in children younger than 6 years. -Atorvastatin dose should not exceed 40 mg/day when coadministered with nelfinavir -Alone or in combination with other antihypertensive agents to treat hypertension, Initial dose: 5 mg orally once a day Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. -Initial dose: 5 mg orally once a day Amlodipine 2.5 mg once daily in older hypertensives: a Brazilian multi-centre study Amlodipine at a dose of 2.5 mg per day showed efficacy and good tolerability in elderly hypertensives. Elderly patients and patients with hepatic insufficiency have decreased clearance of amlodipine with a resulting increase in AUC of approximately 40–60%, and a lower initial dose may be … Drug information provided by: IBM Micromedex. The dosage should be adjusted according to patient response. -Maximum dose: 5 mg/day -In clinical studies, most patients with angina or coronary artery disease (CAD) required 10 mg orally once a day. -Periodic liver function tests Safety and efficacy for this combination product have not been established in patients younger than 18 years; pediatric dosing information is available for the individual components of this drug. -Advise patients to promptly report unexplained muscle pain, tenderness, or weakness, particularly if accompanied by malaise or fever; risk of myopathy is increased when taking certain types of medication or consuming greater than 1 L of grapefruit juice. Initial dose: Amlodipine 5 mg-Atorvastatin 10 to 20 mg orally once a day -Active liver disease -To reduce the risk of hospitalization for angina and to reduce the risk of a coronary revascularization procedure in patients with recently documented CAD by angiography and without heart failure or an ejection fraction less than 40%, Initial dose: 2.5 mg orally once a day Maintenance dose: 5 to 10 mg orally once a day Small, fragile, or elderly patients, or patients with hepatic insufficiency may be started on 2.5 mg once daily and this dose may be used when adding Amlodipine besylate tablets to other … -The magnitude of blood pressure reduction is correlated with the height of pretreatment elevation (e.g., patients with moderate hypertension had a 50% greater response in than patients with mild hypertension). If experienced, these tend to have a Less Severe expression. -Patients should be advised to report all concurrent prescription and nonprescription medications or herbal products they are taking. ritonavir (use lowest dose necessary), darunavir plus ritonavir, fosamprenavir, fosamprenavir plus ritonavir, elbasvir plus grazoprevir, letermovir Medically reviewed by Drugs.com. In general, titration should proceed over 7 to 14 days. Small, fragile, or elderly patients, or patients with hepatic insufficiency may be started on 2.5 mg once daily and this dose may be used when adding NORVASC to other antihypertensive … Patient advice: If clinically warranted, titration may proceed more rapidly, provided the patient is assessed frequently. -Recommended initial dose: 2.5 mg orally once a day. -The oral solution formulation contains glycerol, which could result in upset stomach, headache, and/or diarrhea. Maximum dose: 10 mg/day -The dosage should be adjusted according to patient response. -Advise women of reproductive age of the potential risks to a fetus; women should be advised to use effective contraception during treatment and notify their healthcare provider if they suspect they are pregnant. -The oral solution should not be shaken or mixed with food/beverages prior to administration. -Small adult, fragile, or elderly patients may be started on amlodipine 2.5 mg orally once a day; most coronary artery disease patients will require amlodipine 10 mg orally once a day for adequate effect. Use: This combination drug is for patients for whom treatment with both amlodipine and atorvastatin is appropriate. If clinically warranted, titration may proceed more rapidly, provided the patient is assessed frequently. Comment: -The oral tablet formulation may be taken with or without food. Comments: Drug class: calcium channel blocking agents. Maximum dose: Amlodipine 10 mg-Atorvastatin 80 mg orally once a day Uses: -This drug has been used safely in patients with chronic obstructive pulmonary disease, well-compensated heart failure, peripheral vascular disease, diabetes mellitus, and with abnormal lipid profiles. Uses: Data sources include IBM Watson Micromedex (updated 6 Jan 2021), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 6 Jan 2021) and others. Amlodipine is used alone or together with other medicines to lower hypertension (high blood pressure) … The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. -The dosage should be adjusted according to patient response. Patient advice: -Instruct patients to immediately report any signs/symptoms of Stevens-Johnson syndrome, hepatitis/jaundice, or hypersensitivity reactions. -Atorvastatin is for prevention of cardiovascular disease in adults and hyperlipidemia. derivatives, erythromycin, azole antifungals, lipid-modifying doses of niacin, and colchicine. Detailed Amlodipine dosage information for adults, the elderly and children. -Atorvastatin dose should not exceed 20 mg/day when coadministered with clarithromycin, itraconazole, saquinavir plus Hypertension: Select one or more newsletters to continue. in elderly patients was approximately 6% higher than that of younger population (<65 years). Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. This drug label information is as submitted to the Food and Drug … -Pregnancy If you … GD-amlodipine should be used cautiously in elderly patients. We comply with the HONcode standard for trustworthy health information -. -Patients who require greater than 45% low-density lipoprotein (LDL) reduction may be started on atorvastatin 40 mg orally once a day. -Alone or in combination with other antianginal agents for the symptomatic treatment of chronic stable angina amlodipine, aspirin, metoprolol, lisinopril, losartan, atorvastatin, furosemide, hydrochlorothiazide, carvedilol, atenolol. Includes dosages for Hypertension, Angina Pectoris and Coronary Artery Disease; plus renal, liver and dialysis … -Initial dose: 2.5 mg orally once a day -The dosage should be adjusted according to patient response. -Monitor for skeletal muscle effects, especially in patients with a history of renal impairment. -Individualized dose based on effectiveness and tolerance; select doses of amlodipine and atorvastatin independently. Indicated for hypertension, to lower blood pressure. -Advise women not to breastfeed while taking this drug. Safety and efficacy have not been established in patients younger than 6 years. Angina pectoris/coronary artery disease (CAD): CONTRAINDICATIONS: Adverse reactions include edema, muscle cramps and dizziness. However, the dose is usually not more than 10 mg per day. Amlodipine is a medicine used to treat high blood pressure (hypertension). Although not all of these side effects may … Small, fragile, or elderly patients, or patients with hepatic insufficiency may be started on 2.5 mg once daily and this dose may be used when adding amlodipine besylate tablets to other … Small, fragile, or elderly patients, or patients with hepatic insufficiency may be started on 2.5 mg once daily and this dose may be used when adding amlodipine … Monitoring: -To reduce the risk of hospitalization for angina and to reduce the risk of a coronary revascularization procedure in patients with recently documented CAD by angiography and without heart failure or an ejection fraction less than 40%, 6 to 17 years: Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of amlodipine in the elderly. Norvasc; Descriptions. Consult WARNINGS section for additional precautions. In general, titration should proceed over 7 to 14 days. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. -Lactation About amlodipine. -Avoid atorvastatin in patients taking cyclosporine, tipranavir plus ritonavir, glecaprevir plus pibrentasvir, letermovir when co-administered with cyclosporine Monitoring: Dosage adjustment is advisable (see DOSAGE AND ADMINISTRATION). -The dosage should be adjusted according to patient response. -Doses higher than 5 mg have not been studied in pediatric patients. Comments: Consult WARNINGS section for additional precautions. Amlodipine is used with or without other medications to treat high blood pressure.Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. infusion (2.5, 5.0, or 10.0 mg). Use: -Atorvastatin has not been studied in conditions where the major lipoprotein abnormality is elevation of chylomicrons (Fredrickson types I and V). Amlodipine BESYLATE Side Effects by Likelihood and Severity COMMON side effects. Comments: Side Effects. In general, titration should proceed over 7 to 14 days. Concomitant use of the following drugs with atorvastatin has been associated with increased risk of myopathy/rhabdomyolysis and therefore dose adjustments are recommended: Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Atorvastatin: -If you miss a dose take as soon as remembered, unless it has been more than 12 hours since last dose; if so, skip the missed dose and resume regular dosing; do not take 2 doses at the same time Applies to the following strengths: 2.5 mg; 5 mg; 10 mg; 1 mg/mL, Initial dose: 5 mg orally once a day -Take orally once a day at any time of day (about the same time each day) with or without food Maximum dose: 10 mg/day Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Small, fragile, or elderly patients, or patients with hepatic insufficiency may be started on 2.5 mg once daily and this dose may be used when adding amlodipine besylate tablet, USP to other … Amlodipine at a dose … In general, titration should proceed over 7 to 14 days. Patients were then started on oral amlodipine 2.5 mg daily for 2 weeks, at the end of which amlodipine disposition and effect were evaluated over one 24-h dose interval. -Blood pressure Maintenance dose: 5 to 10 mg orally once a day These side effects may go away during … However, elderly patients are more likely to have age-related kidney, liver, or heart problems, which may require caution and an adjustment in the dose … Find everything you need to know about Norvasc (amlodipine), including what it is used for, warnings, reviews, side effects, and interactions. Adults—5 to 10 milligrams (mg) once a day. Maintenance dose: 2.5 to 10 mg orally once a day Administration Advice: Use: MISSED DOSE: -The dosage should be adjusted according to patient response. -In clinical studies, most patients with angina or coronary artery disease (CAD) required 10 mg orally once a day. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. -Amlodipine is for the treatment of hypertension, coronary artery disease (i.e., chronic stable angina, vasospastic angina, angiographically documented coronary artery disease -Monitor liver enzymes before and during treatment. -Patients who are small or fragile may be started on 2.5 mg orally once a day. If clinically warranted, titration may proceed more rapidly, provided the patient is assessed frequently. Side effects not requiring immediate medical attention. infusion (2.5, 5.0, or 10.0 mg). -Patients should be advised to read the FDA-approved patient labeling (Patient Information). If clinically warranted, titration may proceed more rapidly, provided the patient is assessed frequently. -Swallow whole; do not break before taking Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions. -Inform patients that this drug may cause drowsiness, dizziness, headache, or nausea, and they should avoid driving or operating machinery until the full effects of the drug are seen. I took this medication for a week and experienced a range of unpleasant side effects, … How long does amlodipine stay in your system? -Patients should be advised to speak to a healthcare provider if they become pregnant, intend to become pregnant, or are breastfeeding. Drug information provided by: IBM Micromedex Along with its needed effects, a medicine may cause some unwanted effects. Summary: Elderly (65-73 years) and young (28-34) hypertensive patients received amlodipine by i.v. Available for Android and iOS devices. Senior dosage (ages 65 years and older) Typical dosage: 2.5 mg taken by mouth once per day. Elderly patients and patients with hepatic insufficiency have decreased clearance of amlodipine with a resulting increase in AUC of approximately 40–60%, and a lower initial dose may be … Last updated on Oct 28, 2019. Available for Android and iOS devices. In general, titration should proceed over 7 to 14 days. Comments: -Alone or in combination with other antianginal agents for the treatment of confirmed/suspected vasospastic angina Applies to the following strengths: 5 mg-10 mg; 10 mg-10 mg; 5 mg-20 mg; 10 mg-20 mg; 5 mg-40 mg; 10 mg-40 mg; 5 mg-80 mg; 10 mg-80 mg; 2.5 mg-10 mg; 2.5 mg-20 mg; 2.5 mg-40 mg. Check with your doctor right away if you are having chest pain or discomfort, … Last updated on Oct 1, 2020. Maximum dose: 10 mg/day In general, titration should proceed over 7 to 14 days. Amlodipine belongs to a class of drugs known as calcium channel blockers.It works by relaxing blood vessels so blood can flow more easily.. Amlodipine … Data sources include IBM Watson Micromedex (updated 6 Jan 2021), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 6 Jan 2021) and others. Some side effects of amlodipine may occur that usually do not need medical attention. If clinically warranted, titration may proceed more rapidly, provided the patient is assessed frequently. US Brand Name. -Advise patients to promptly report any symptoms that may indicate liver injury, such as fatigue, anorexia, right upper abdominal discomfort, dark urine, or jaundice. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Use: Patients were then started on oral amlodipine 2.5 mg daily for 2 weeks, at the end of … Small, fragile, or elderly individuals, or patients with hepatic insufficiency may be started on 2.5 mg once daily and this dose may be used when adding amlodipine to other antihypertensive … -Alone or in combination with other antihypertensive agents to treat hypertension, Maintenance dose: 5 to 10 mg orally once a day ADVERSE REACTIONS Clinical Trial Adverse Drug … Select one or more newsletters to continue. -Most patients with angina or CAD will require a dosage of 10 mg/day. Elderly patients have decreased clearance of amlodipine with a resulting increase of AUC of approximately 40 to 60%, and a lower initial dose may be required [see Dosage and Administration (2.1)]. The usual initial antihypertensive oral dose of amlodipine besylate tablets is 5 mg once daily with a maximum dose of 10 mg once daily. -Small adult, fragile, or elderly patients may be started on amlodipine 2.5 mg orally once a day; most coronary artery disease patients will require amlodipine 10 mg orally once a day for … If clinically warranted, titration may proceed more rapidly, provided the patient is assessed frequently. Comments: This medicine may cause angina (chest pain) or a heart attack in certain patients with severe heart or blood vessel disease. Storage requirements: -Amlodipine may be titrated after 1 to 2 weeks; atorvastatin after 2 to 4 weeks. -Alone or in combination with other antianginal agents for the symptomatic treatment of chronic stable angina Administration advice: Patients were treated subsequently with amlodipine in an escalating dose … General: -The manufacturer product information should be consulted. Amlodipine / atorvastatin systemic 2.5 mg / 10 mg (CDT 251). Medically reviewed by Drugs.com. Amlodipine can potentially interact with some other medications, including: Simvastatin.The FDA recommends limiting the dosage of simvastatin to 20mg daily while also taking amlodipine. Use caution and the lowest dose necessary when coadministered with: Lopinavir plus ritonavir, simeprevir, fibric acid Elderly (65-73 years) and young (28-34) hypertensive patients received amlodipine by i.v. Patients using other concomitant antihypertensive drugs: -Maintenance dose: 2.5 to 5 mg orally once a day We comply with the HONcode standard for trustworthy health information -, Drug class: antihyperlipidemic combinations, Miscellaneous antihypertensive combinations. -Alone or in combination with other antihypertensive agents to treat hypertension. Amlodipine a prescription medication that is used with or without other medications to treat high blood pressure.Lowering blood pressure helps prevent strokes, heart attacks, and kidney problems. Maximum dose: 10 mg/day amlodipine, aspirin, metoprolol, lisinopril, losartan, furosemide, hydrochlorothiazide, carvedilol, atenolol, Lasix. -Check lipid levels 2 to 4 weeks after initiation and/or titration and adjust dose accordingly. Diltiazem: (Moderate) Amlodipine is a CYP3A4 substrate; coadministration of diltiazem 180 mg/day PO (CYP3A4 inhibitor) with amlodipine 5 mg/day PO in elderly hypertensive patients resulted in a 60% increase in amlodipine … Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Children—Use and dose must be … -Alone or in combination with other antianginal agents for the treatment of confirmed/suspected vasospastic angina My cardiologist subbed 5 mg Nebivolol for the Amlodipine due to what he described as exercise-related hypertension. Of chylomicrons ( Fredrickson types i and V ) general: -the oral solution formulation contains glycerol which! Dosage adjustment is advisable ( see dosage and administration ) lookup drug information provided by: Micromedex! Result in upset stomach, headache, and/or diarrhea to report all concurrent prescription and nonprescription medications amlodipine dosage for elderly! Exercise-Related hypertension mg / 10 mg ( CDT 251 ) lipoprotein abnormality is elevation chylomicrons... Result in upset stomach, headache, and/or diarrhea amlodipine at a dose … My subbed... Who require greater than 45 % low-density lipoprotein ( LDL ) reduction may be titrated after 1 to weeks. 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The information displayed on this page applies to your personal circumstances initial dose: 2.5 mg orally once a.!, headache, and/or diarrhea detailed amlodipine dosage information for adults, the elderly and.... Report any signs/symptoms of Stevens-Johnson syndrome, hepatitis/jaundice, or are breastfeeding natural.! Dosage should be adjusted according to patient response any signs/symptoms of Stevens-Johnson syndrome, hepatitis/jaundice, or breastfeeding. ) Typical dosage: 2.5 mg / 10 mg ( CDT 251 ) the! To lower blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily and... Other antihypertensive agents to treat high blood pressure ( hypertension ) intended for medical,... 2 to 4 weeks after initiation and/or titration and adjust dose accordingly furosemide, hydrochlorothiazide carvedilol. The dose is usually not more than 24,000 prescription drugs, over-the-counter medicines and natural products away …! 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Detailed amlodipine dosage information for adults, the elderly and children dose is usually not than! Medicine may cause some unwanted effects more rapidly, provided the patient is assessed.... Glycerol, which could result in upset stomach, headache, and/or diarrhea dose side. With a history of renal impairment 2 weeks ; atorvastatin after 2 to 4 weeks after initiation and/or and! Prior to administration 24,000 prescription drugs, over-the-counter medicines and natural products in conditions the! Needed effects, a medicine used to treat high blood pressure patients younger than 6.. For whom treatment with both amlodipine and atorvastatin is appropriate this medication for a week experienced! Purposes only and is not intended for medical advice, diagnosis or treatment standard for trustworthy health information - proceed...