From outside to inside (dermis). The epidermis is the outer layer of cells that cover an organism. Learn vocabulary, terms, and more with flashcards ... Key Concepts: Terms in this set (50) finger-like processes that fold down from the epidermis into the dermis. Learn vocabulary, terms, and more with flashcards, games, and other study tools. There are two layers of epidermis, the living basal layer, which is next to the dermis, and the external stratum corneum, or horny layer, which is composed of dead, keratin-filled cells that have migrated outward from the basal layer. - Skin is the largest organ in the body (15-20% of your body weight), - Protective (physical barrier against microorganisms, physical insults, water loss or uptake, and UV radiation. Figure 1. rete pegs. -Mutations in type I, III and V collagen cause different types of Ehler-Danlos syndrome, -Mutations in elastin found in families with cutis laxa, -Loose, redundant skin that is inelastic, lacks recoil, and results in "hound dog" facies, -Vitamin C deficiency resulting in problems with collagen synthesis, -Decreased compliance and elastic due to fibroblasts, -Excessive ECM--> thickened and fibrotic skin, -Sole goal is to make substances and secrete them, -Type III collagen (more in papillary region). The epidermis can be impacted by more than just injury. What are factors that increase melanin production? The dermis has two regions: the Papillary Dermis and; the Reticular Dermis. - Dermal papillae in papillary layer of the dermis interdigitate with epidermal ridges or pegs, thereby increasing the surface area of contact between the epidermis and dermis. The epidermis also contains desmosomes. Its thickness varies depending on the location of the skin. The epidermis is divided into 5 sub-layers, that have different functions. Dermis and epidermis both act as the protective outer layer of the body and are very important components of our body. - Pigments include melanin and carotene (also influenced by epidermal thickness and vascularization of dermis). The epidermis does not contain blood vessel whereas dermis contains capillaries beneath the epidermis. Learn vocabulary, terms, and more with flashcards, games, and other study tools. Cells in the epidermis divide and move up to replace cells in the layers above, changing as they move from one layer to the next. What connects the dermis to the epidermis? -Netlike appearance of vascular perfustion, -Normal vasoconstriction of proximal arterioles. Then there are the melanocytes, which are produced by the corns of the color, substance melanin that gives tone to the skin. It looks like your browser needs an update. Start studying Dermis. This outermost layer is subject to both genetics and external forces that contribute to the aging of this skin. - 2 mitotic layers are the stratum spinosum, and stratum basale, - Increased proliferation of karatinocytes in stratum basale and spinosum (stimulated by activated T cells). What is unique about the dermal-epidermal junction? Stratum corneum: The outmost layer, made of dead keratinocytes with a layer of protein … All but the deepest layers are composed of dead cells. In which layers does melanin deposit into keratinocytes, and how is this done? What are the five layers of the Epidermis, as well as the underlying layer below the epidermis? The dermis of animals is found in the skin and is made up of dense irregular connective tissue. Start studying epidermis dermis and hypodermis. Start studying Layers and Characteristics of the Dermis. Birds and mammals are endothermic animals. The Dermis • Is located between epidermis and subcutaneous layer • Anchors epidermal accessory structures (hair follicles, sweat glands) • Has 2 layers: – outer papillary layer – deep reticular layer Characteristics of Dermis Dense Irregular Connective Tissue Strat… The epidermis is highly keratinized, mostly dead, stratified squamous epithelium. The epidermisis composed of keratinized, stratified squamous epithelium. What are the key histological characteristics of the stratum granulosum, as well as other important features? - separated from the underlying dermis by a basement membrane - not as thick as the dermis - contains no blood vessels - living cells of the epidermis receive nutrients and excrete waste products by diffusion of substances between the epidermis and the capillaries of the dermis - … - Composed of keratinized stratified squamous epithelium. Learn vocabulary, terms, and more with flashcards, games, and other study tools. It's located between the epidermis and the subcutaneous tissue. - 3-5 layers of flattened polygonal cells. It is the layer that holds all the blood vessels, nerves, hair follicles, collagen and sweat glands. - Many layers of dead, platelike enucleate keratinocytes. Structure: Deep part of skin; connective tissue composed of two layers. What are keratinocytes specifically, and how are they derived? The dermis is the thickest layer of skin, and a fibrous structure composed of collagen, elastic tissue, and other extracellular components including vasculature, nerve endings, hair follicles, and glands. - Composed of well-vascularized connnective tissue. Skin that has four layers of cells is referred to as “thin skin.” From deep to superficial, these layers are the stratum basale, stratum spinosum, stratum granulosum, and stratum corneum. Act as the protective outer layer of the epidermis to the aging of this skin layer has connective tissues blood! 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